Human Type 1 IFN Neutralizing Antibody Mixture
品牌:PBL Assay Science
规格:0.2 ml
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Product Features: 
  • Mixture of monoclonal and polyclonal antibodies directed against human Type 1 Interferons (IFNs) and Type 1 Receptor Subunit 2 (IFNAR2)
  • Effectively neutralizes biological activity of human IFN-alpha, IFN-beta, IFN-omega, IFN-kappa, and IFN-epsilon
  • Improves neutralization of multiple Type I IFNs often found in complex samples by employing a broadly neutralizing custom antibody cocktail
  • Unconjugated

Formulation Supplied frozen in phosphate-buffered saline (PBS)
Purification A combination of Protein G affinity chromatography and other conventional chromatographical methods.
Endotoxin level < 1 EU/μg
Bioactivity Encephalomyocarditis Virus (EMCV) was used to challenge A549 cells which were incubated with a constant concentration of the antibody mixture and the titrated interferon.
Specificity Blocks biological activity of human Type I interferons (alpha, beta, omega, kappa, epsilon)
No cross reactivity observed with the following human interferons: gamma, lambda 1, lambda 2, lambda 3; or mouse interferons: alpha, beta, gamma
Storage For retention of full activity store at -70°C or below and avoid repeated freeze/thaw cycles
Synonyms Type I interferon, Type I IFN, Neutralizing, Neutralization, Type I Interferon Receptor, Antibody Cocktail